Clinical utility of circulating calprotectin to assist prediction and monitoring of COVID-19 severity: An Italian studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] 바이오마커, [키워드] Administered Admission assist Biomarker calprotectin Care chemiluminescent immunoassay circulating Circulating calprotectin clinical Cohort collected Concentration controls correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease severity evaluate healthy individual ICU intubation Italian study median Patient positive airway pressure Respiratory Support risk risk assessment. Sample serological serum severity of COVID-19 Severity of disease significantly higher tested utility were used [DOI] 10.1002/jmv.28056 PMC 바로가기
Could red cell distribution width be used for predicting cardiac injury in neonates with COVID-19?Article Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Affect all age group calculated coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 pandemic COVID-19 cut-off value determine Diagnosis died Diseases distribution Fever group Hospitalization illness immature immunologically Inflammation Inflammatory Injury Laboratory life-threatening management nasopharyngeal swab sample Neonatal Neonate Neonates Newborn Patient PCR PCR-positive polymerase chain populations positive Prognosis prognostic prognostic biomarker Prognostic value Red cell Red cell distribution width SARS-CoV-2 SARS-COV-2 infection screened Sensitivity and specificity severe disease significantly higher syndrome systemic inflammatory the patient troponin level troponin levels troponin. were used [DOI] 10.1002/jmv.28050 PMC 바로가기
The capacity to adapt: Documenting the relationship between stressors and probable depression, anxiety, and posttraumatic stress at two time points during the COVID-19 pandemicResearch article Published on 2022-12-012022-10-05 Journal: Journal of affective disorders [Category] 진단, [키워드] ANOVA Anxiety Assets categories changes in COVID-19 COVID-19 pandemic cross-sectional Depression diagnoses Diagnosis diagnostic distribution Documenting finding higher odd highlight limitation medium post-traumatic Post-traumatic stress Posttraumatic Stress Prevalence Psychiatric PTS reduction Regression Result skewed Stress stress levels Stressor stressors Symptom symptom severity variables were measured were used [DOI] 10.1016/j.jad.2022.08.120 [Article Type] Research article
COVID-19 and the injured patient: A multicenter reviewResearch article Published on 2022-12-012022-10-05 Journal: The Journal of surgical research [Category] 바이오마커, [키워드] adverse events Affect age Analysis baseline characteristics C-reactive protein Coagulopathy Cohort collected Comorbidities composed Coronavirus disease 2019 COVID-19 cumulative D-dimer demographics diabetes events ferritin Frame Hospitalization hypertension In-hospital death Injury ISS Kaplan–Meier method log-rank test median morbidity and mortality Mortality multicenter neurologic New York Older outcome outcomes Patient patients performed physiological Primary outcome Result Retrospective analysis severity shown study period surgical tested trauma trauma patient trauma patients were excluded were used [DOI] 10.1016/j.jss.2022.06.068 [Article Type] Research article
Rapid detection of SARS-CoV-2 variants of concern by single nucleotide polymorphism genotyping using TaqMan assaysArticle Published on 2022-12-012022-11-15 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome approach B.1.1.7 B.1.526 clinical setting Concordance coronavirus coronavirus disease 19 Coronavirus disease 19 (COVID-19) E484K evaluated genotyping mutations N501Y nasopharyngeal Negative predictive value New York City nonsynonymous patient population polymorphism positive positive sample predicted ranged Rapid Real-time reverse-transcription PCR residual RT-qPCR SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2 variant sensitivity Sequencing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significantly lower single nucleotide specificity Spike protein submitted subset TaqMan TaqMan assay Thermofisher variant variants variants of concern. were used WGS whole genome [DOI] 10.1016/j.diagmicrobio.2022.115789 PMC 바로가기
Ultrarapid and ultrasensitive detection of SARS-CoV-2 antibodies in COVID-19 patients via a 3D-printed nanomaterial-based biosensing platformArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 3D biosensor 3D printing Additive manufacturing antibody Antibody detection coated with Concentration COVID-19 COVID-19 antibodies COVID-19 patient COVID-19 patients Critical detected antibody disease domain Efficacy Epidemics Epidemiology evaluate Gold nanoparticle Graphene oxide human plasma samples immune response Immunity Infection Interaction manuscript nucleocapsid Outbreaks Patient patients without COVID-19 platform Quantitative Rapid rapid antibody detection. rapid antibody test RBD reported SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigens serological Spike protein the antibodies the N protein vaccination Vaccine Viral protein were used [DOI] 10.1002/jmv.28075 PMC 바로가기
Protection against Omicron from Vaccination and Previous Infection in a Prison SystemArticle Published on 2022-11-102022-11-16 Journal: The New England Journal of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Analysis B.1.1.529 B.1.617.2 booster collected Combination coronavirus Cox model dose doses effective Effectiveness estimate evaluate evaluated hazard ratio high-risk population Infection mRNA mRNA vaccination mRNA vaccine offered omicron Omicron variant prison protection ranged retrospective cohort risk of infection SARS-CoV-2 significantly more stratified System vaccination vaccine dose vaccine doses variant were used [DOI] 10.1056/NEJMoa2207082 PMC 바로가기
Covid-19 vaccination programme effectiveness against SARS-CoV-2 related infections, hospital admissions and deaths in the Apulia region of Italy: a one-year retrospective cohort studyArticle Published on 2022-11-032022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] Ad26.COV2.S vaccine Alpha Apulia calculate ChAdOx1-S Cohort combined use conducted COVID-19 COVID-19 infection COVID-19 infections COVID-19 vaccination COVID-19 vaccination programme Cox regression model death deaths Delta variants dominant Effect Effectiveness Effects Electronic health record eligible estimate hazard ratio Hospital admission hospitalisation infections Italy mRNA-1273 of BNT162b2 Older outcome positive Protective reduced retrospective cohort study SARS-CoV-2 SARS-CoV-2 infections study period subject vaccination Vaccine variant variants waned were used yielding [DOI] 10.1038/s41598-022-23235-4 PMC 바로가기
Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasionArticle Published on 2022-11-012022-11-15 Journal: Food and chemical toxicology : an international jo [Category] SARS, 변종, 치료제, [키워드] analyzed anti-SARS-CoV-2 antiviral effects binding caused complexes component components demonstrated exhibit FRET test Ganoderma lucidum triterpenoids hACE2 hACE2 receptor high affinity hydrogen bonds IC50 in vitro Infection inhibit inhibited inhibition assay Invasion Lucidenic acid A (PubChem CID: 14109375) molecular docking molecular dynamics Mutation natural natural products omicron Omicron variant omicron variant. pathway Potential Prevent PubChem receptor receptor proteins SARS-CoV-2 Spike protein stability target variant Virtual screening virus was selected were used [DOI] 10.1016/j.fct.2022.113438 PMC 바로가기
Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detectionArticle Published on 2022-11-012022-11-15 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료기술, [키워드] amplification Antigen automated collected cycle threshold detect diagnostic early stage evaluated healthcare Measures NAAT nasal swab nasal swabs Nasopharyngeal swab nasopharyngeal swabs negative correlation nine NPs nucleic acid amplification nucleic acid amplification test patients with COVID-19 positive Quantitative Quantitative SARS-CoV-2 antigen test Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection significantly significantly higher significantly lower symptom onset tested Viral load Viral load. were used [DOI] 10.1016/j.jiac.2022.07.023 PMC 바로가기